The keynote will be presented at the Yerba Buena Center for the Arts in San Francisco at 10 am PDT.
The invite includes a graphic stating "It's only rock and roll, but we like it," which references a classic Rolling Stones lyric.
The event is rumored to bring a refresh to the entire iPod lineup. iTunes could also see an update to version 9 which is said to include new social features.
According to recent reports, Its unlikely that a Apple will announce a new tablet device at this event.